BDBM307846 (3R)-N-{5-chloro-4-[1-(3-fluorobenzyl)-2-methyl-1H-benzimidazol-6-yl]pyridin-2-yl}piperidine-3-carboxamide::US9650358, Example 142

SMILES Cc1nc2ccc(cc2n1Cc1cccc(F)c1)-c1cc(NC(=O)[C@@H]2CCCNC2)ncc1Cl

InChI Key InChIKey=LBQOJCDURHHRIK-LJQANCHMSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 307846   

TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM307846((3R)-N-{5-chloro-4-[1-(3-fluorobenzyl)-2-methyl-1H...)
Affinity DataIC50:  30nMAssay Description:CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent