BDBM307848 (3R)-N-(5-chloro-4-{1-[(1R)-1-(3-fluorophenyl)ethyl]-1H-benzimidazol-6-yl}pyridin-2-yl)piperidine-3-carboxamide::US9650358, Example 144

SMILES C[C@H](c1cccc(F)c1)n1cnc2ccc(cc12)-c1cc(NC(=O)[C@@H]2CCCNC2)ncc1Cl

InChI Key InChIKey=PAAMOALCRCFZRX-VQIMIIECSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 307848   

TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM307848( (3R)-N-(5-chloro-4-{1-[(1R)-1-(3-fluorophenyl)eth...)
Affinity DataIC50:  19nMAssay Description:CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent