BDBM307882 (3R)-N-[5-chloro-4-(1-{[3-(pyrrolidin-1-yl)oxetan-3-yl]methyl}-1H-benzimidazol-6-yl)pyridin-2-yl]piperidine-3-carboxamide::US9650358, Example 178

SMILES Clc1cnc(NC(=O)[C@@H]2CCCNC2)cc1-c1ccc2ncn(CC3(COC3)N3CCCC3)c2c1

InChI Key InChIKey=YZVZGMUZKKBRMI-LJQANCHMSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 307882   

TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM307882( (3R)-N-[5-chloro-4-(1-{[3-(pyrrolidin-1-yl)oxetan...)
Affinity DataIC50:  16nMAssay Description:CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent