BDBM307935 trans-N-{5-chloro-4-[1-(3-fluorobenzyl)-1H-benzimidazol-6-yl]pyridin-2-yl}-N′-[2-(morpholin-4-yl)ethyl]cyclohexane-1,4-diamine::US9650358, Example 231

SMILES Fc1cccc(Cn2cnc3ccc(cc23)-c2cc(N[C@H]3CC[C@@H](CC3)NCCN3CCOCC3)ncc2Cl)c1

InChI Key InChIKey=ZBXPWTBEBURANX-DIVCQZSQSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 307935   

TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM307935( trans-N-{5-chloro-4-[1-(3-fluorobenzyl)-1H-benzim...)
Affinity DataIC50:  36nMAssay Description:CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent