BDBM308023 (3R)-N-{5-chloro-4-[1-(3-fluorobenzyl)-5-methoxy-1H-benzimidazol-6-yl]pyridin-2-yl}piperidine-3-carboxamide ::US9650358, Example 319

SMILES COc1cc2ncn(Cc3cccc(F)c3)c2cc1-c1cc(NC(=O)[C@@H]2CCCNC2)ncc1Cl

InChI Key InChIKey=LBJBFDISKVOONG-QGZVFWFLSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 308023   

TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM308023( (3R)-N-{5-chloro-4-[1-(3-fluorobenzyl)-5-methoxy-...)
Affinity DataIC50:  21nMAssay Description:CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent