BDBM310122 2,6-difluoro-N-(5-(4-fluorobenzenesulfonyl)-5,6,7,8-tetrahydro-[1,5]naphthyridin-3-yl)benzamide ::US10377768, Compound 36::US9657033, Compound 36

SMILES Fc1ccc(cc1)S(=O)(=O)N1CCCc2ncc(NC(=O)c3c(F)cccc3F)cc12

InChI Key InChIKey=GQJTWQAQVTVAQA-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 310122   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Lycera

US Patent
LigandPNGBDBM310122(2,6-difluoro-N-(5-(4-fluorobenzenesulfonyl)-5,6,7,...)
Affinity DataEC50:  700nMAssay Description:Recombinant,HIS-tagged RORγ-LBD was expressed in SF9 cells using a baculovirus expression system. Cells were lysed and the lysate was used as a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Lycera

US Patent
LigandPNGBDBM310122(2,6-difluoro-N-(5-(4-fluorobenzenesulfonyl)-5,6,7,...)
Affinity DataEC50:  202nMAssay Description:HIS-tagged RORγ-LBD protein was expressed in SF9 cells using a baculovirus expression system. The RORγ-LBD protein was purified by glutathi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Lycera

US Patent
LigandPNGBDBM310122(2,6-difluoro-N-(5-(4-fluorobenzenesulfonyl)-5,6,7,...)
Affinity DataEC50:  700nMAssay Description:Recombinant, HIS-tagged RORγ-LBD was expressed in SF9 cells using a baculovirus expression system. Cells were lysed and the lysate was used as a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Lycera

US Patent
LigandPNGBDBM310122(2,6-difluoro-N-(5-(4-fluorobenzenesulfonyl)-5,6,7,...)
Affinity DataEC50:  202nMAssay Description:HIS-tagged RORγ-LBD protein was expressed in SF9 cells using a baculovirus expression system. The RORγ-LBD protein was purified by glutathi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent