BDBM310919 6-Bromo-5-(Difluoro(Phosphonato)Methyl)Benzo[b]Thiophene-2-Carboxylate::US10150787, Example 2::US11597739, Example 2

SMILES OC(=O)c1cc2cc(c(Br)cc2s1)C(F)(F)P(O)(O)=O

InChI Key InChIKey=TYTJRJKCKZRLFW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 310919   

TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
The Royal Institution For The Advancement of Learning/Mcgill University

US Patent
LigandPNGBDBM310919(6-Bromo-5-(Difluoro(Phosphonato)Methyl)Benzo[b]Thi...)
Affinity DataIC50:  260nMAssay Description:Activity of the compounds of this application may be evaluated using the following assays for TC-PTP-inhibiting activity. Compounds of Formula I will...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
The Royal Institution For The Advancement of Learning/Mcgill University

US Patent
LigandPNGBDBM310919(6-Bromo-5-(Difluoro(Phosphonato)Methyl)Benzo[b]Thi...)
Affinity DataIC50:  260nMAssay Description:The assay was carried out at room temperature in 96 well plates. The reaction mixture in 170 μl contained 50 mM Bis-Tris (pH=6.3), 2 mM EDTA, 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent