BDBM310923 ((6-Bromo-2-(Cyanomethyl)Benzo[b]Thiophen-5-yl)Difluoromethyl)Phosphonate::US10150787, Example 6::US11597739, Example 6

SMILES OP(O)(=O)C(F)(F)c1cc2cc(CC#N)sc2cc1Br

InChI Key InChIKey=YJDMADZYBBEOOW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 310923   

TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
The Royal Institution For The Advancement of Learning/Mcgill University

US Patent
LigandPNGBDBM310923(((6-Bromo-2-(Cyanomethyl)Benzo[b]Thiophen-5-yl)Dif...)
Affinity DataIC50:  370nMAssay Description:Activity of the compounds of this application may be evaluated using the following assays for TC-PTP-inhibiting activity. Compounds of Formula I will...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
The Royal Institution For The Advancement of Learning/Mcgill University

US Patent
LigandPNGBDBM310923(((6-Bromo-2-(Cyanomethyl)Benzo[b]Thiophen-5-yl)Dif...)
Affinity DataIC50:  370nMAssay Description:The assay was carried out at room temperature in 96 well plates. The reaction mixture in 170 μl contained 50 mM Bis-Tris (pH=6.3), 2 mM EDTA, 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent