BDBM310926 ((5-Bromo-2-(Carboxy)Benzo[b]Thiophen-6-yl)Difluoromethyl)Phosphonate::US10150787, Example 9::US11597739, Example 9

SMILES OC(=O)c1cc2cc(Br)c(cc2s1)C(F)(F)P(O)(O)=O

InChI Key InChIKey=NVKUMOGTOCQWSD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 310926   

TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
The Royal Institution For The Advancement of Learning/Mcgill University

US Patent
LigandPNGBDBM310926(((5-Bromo-2-(Carboxy)Benzo[b]Thiophen-6-yl)Difluor...)
Affinity DataIC50:  170nMAssay Description:Activity of the compounds of this application may be evaluated using the following assays for TC-PTP-inhibiting activity. Compounds of Formula I will...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
The Royal Institution For The Advancement of Learning/Mcgill University

US Patent
LigandPNGBDBM310926(((5-Bromo-2-(Carboxy)Benzo[b]Thiophen-6-yl)Difluor...)
Affinity DataIC50:  170nMAssay Description:The assay was carried out at room temperature in 96 well plates. The reaction mixture in 170 μl contained 50 mM Bis-Tris (pH=6.3), 2 mM EDTA, 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent