BDBM31198 spiro-oxindole, 4

SMILES CC(C)(C)C[C@H]1N[C@H]([C@H](c2cccc(Cl)c2)[C@@]11C(=O)Nc2cc(Cl)ccc12)C(=O)NCCN1CCOCC1

InChI Key InChIKey=GXAPJIXXSLQQBJ-ZTVFFDQVSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31198   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

LigandPNGBDBM31198(spiro-oxindole, 4)
Affinity DataKi:  13nM ΔG°:  -10.7kcal/molepH: 7.5 T: 2°CAssay Description:The dose-dependent binding experiments were carried out with serial dilutions of the tested compounds in DMSO. A 5 ul sample of the tested samples an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed