BDBM312074 (R)-3-(6-bromo-5- fluoro-1H-indol-3-yl)- pyrrolidine-2,5-dione::US9603836, Compound 10::US9949951, 10
SMILES Fc1cc2c(c[nH]c2cc1Br)[C@H]1CC(=O)NC1=O
InChI Key
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 312074
Affinity DataIC50: 620nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
Affinity DataIC50: 620nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 620nMAssay Description:The compounds of the present invention inhibit the enzymatic activity of human IDO1.To measure enzymatic activity of human IDO1, the reaction mixture...More data for this Ligand-Target Pair