BDBM312118 (S)-2-((S)-3,3- Dimethyl-2-((S)-2- (methylamino) propanamido) butanoyl)-N-(4- (((3S,5S)-1-((S)- 3,3-dimethyl-2- ((S)-2-(methyl- amino) propanamido) butanoyl)-5-(((R)- 1,2,3,4-tetra- hydronaphthalen-1- yl)carbamoyl) pyrrolidin- 3-yl)carbamoyl) benzyl)-N-((R)- 1-(2-ethoxyphenyl) ethyl)-1,2,3,4- tetrahydro- isoquinoline- 3-carboxamide::US9603889, Example 29
SMILES CCOc1ccccc1[C@@H](C)N(Cc1ccc(cc1)C(=O)NC1C[C@H](N(C1)C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)C(=O)NC1CCCc2ccccc12)C(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C
InChI Key InChIKey=BZYLXAPGOBAABU-WUBRCICJSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 312118
TargetBaculoviral IAP repeat-containing protein 2/E3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 340nMAssay Description:Assays were performed in white, flat-bottom, 384-well ProxiPlates (Perkin Elmer). The final assay volume was 10 μL prepared from additions of Hi...More data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 3/E3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 160nMAssay Description:Assays were performed in black, flat-bottom, 384-well plates. The final assay volume was 50 μL prepared from additions of N-His-Tb-BIR3(241-356,...More data for this Ligand-Target Pair