BDBM312122 N1-(((S)-2-((S)- 3,3-Dimethyl- 2-((S)-2- (methylamino) propanamido) butanoyl)-1,2,3,4- tetrahydro- isoquinolin- 3-yl)methyl)- N4-((3S,5S)- 1-((S)-3,3- dimethyl-2-((S)-2- (methylamino) propanamido) butanoyl)- 5-(((R)-1,2,3,4- tetrahydro- naphthalen- 1-yl)carbamoyl) pyrrolidin-3-yl)-N1- (2-(naphthalen-1- yl)ethyl) terephthalamide::US9603889, Example 33
SMILES CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@H](C[C@H]1C(=O)N[C@@H]1CCCc2ccccc12)NC(=O)c1ccc(cc1)C(=O)N(CCc1cccc2ccccc12)C[C@@H]1Cc2ccccc2CN1C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)C(C)(C)C
InChI Key InChIKey=UXJVAMCICAERKY-XSURLAPZSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 312122
TargetBaculoviral IAP repeat-containing protein 2/E3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 900nMAssay Description:Assays were performed in white, flat-bottom, 384-well ProxiPlates (Perkin Elmer). The final assay volume was 10 μL prepared from additions of Hi...More data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 3/E3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 120nMAssay Description:Assays were performed in black, flat-bottom, 384-well plates. The final assay volume was 50 μL prepared from additions of N-His-Tb-BIR3(241-356,...More data for this Ligand-Target Pair