BDBM312595 US9604998, Example 1

SMILES COc1cc(ccc1C#N)[C@H]1CN2CCN(C[C@H](O)c3ccc4C(=O)OCc4c3C)C[C@@H]2CO1

InChI Key InChIKey=FTTHKPWKYYBOKS-HFRGRHLUSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 312595   

TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM312595(US9604998, Example 1)
Affinity DataIC50:  110nMAssay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent