BDBM312595 US9604998, Example 1
SMILES COc1cc(ccc1C#N)[C@H]1CN2CCN(C[C@H](O)c3ccc4C(=O)OCc4c3C)C[C@@H]2CO1
InChI Key InChIKey=FTTHKPWKYYBOKS-HFRGRHLUSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 312595
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 110nMAssay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair