BDBM312663 US9604998, Example 63
SMILES O=C1OCc2cc(CCN3CCN4C[C@@H](OC[C@@H]4C3)c3ccc4C(=O)OCc4c3)ccc12
InChI Key InChIKey=JHHCXPGHGOJJKK-NZQKXSOJSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 312663
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 40nMAssay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair