BDBM312667 US9604998, Example 67
SMILES Cc1c2COC(=O)c2ccc1CCN1CCN2C[C@@H](OC[C@H]2C1)c1ccc2C(=O)OCc2c1C
InChI Key InChIKey=UHHLIDSZDXQYRZ-KBMIEXCESA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 312667
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 70nMAssay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair