BDBM31278 Chalcone derivative, E

SMILES CCOC(=O)C(C)(C)Oc1ccc(CCNC(=O)\C=C\C(=O)c2ccc(Cl)cc2)cc1

InChI Key InChIKey=PSLJGGRDWMUPLT-BUHFOSPRSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31278   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Max Planck Institute

LigandPNGBDBM31278(Chalcone derivative, E)
Affinity DataIC50: >2.50E+5nMpH: 7.4 T: 2°CAssay Description:Interference of the p53-MDM2 binding by test compounds was measured in a 96-well polypropylene round-bottom microtiter plate (Costar, Serocluster). H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed