BDBM313905 US10167296, Example 2.16

SMILES COc1c(C)c2c(Nc3ccc(F)cc3O[C@H](C)C(F)(F)F)ncnc2cc1N=S(C)(C)=O

InChI Key InChIKey=XIEAFKODPXAHDN-GFCCVEGCSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 313905   

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Evotec International

US Patent
LigandPNGBDBM313905(US10167296, Example 2.16)
Affinity DataIC50:  3.5nMAssay Description:The inhibition of kinase activity of MNK2a was assessed using pre-activated GST-MNK2a. The white, 384-well OptiPlate F plates were purchased from Per...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent