BDBM313977 US10167299, Example 27

SMILES CC(C)c1nnc(C)n1C1CC2CCC(C1)N2CC[C@H](NC(=O)C1CCC(F)(F)CC1)c1csc2ccccc12

InChI Key InChIKey=BUMYPVOXXHEQEG-LFTRXOAISA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 313977   

TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM313977(US10167299, Example 27)
Affinity DataIC50:  11.4nMAssay Description:1. HEK293 cells which can stably express CCR5 were inoculated in a 96-well plate and incubated overnight.2. The medium in each well into which cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent