BDBM314037 N-[(1S)-3-[exo-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane-8-yl]-1-(5-fluorothiophen-2-yl)propyl]-1-methylsulfonylpiperidine-4-carboxamide::US10167299, Example 151

SMILES CC(C)c1nnc(C)n1C1CC2CCC(C1)N2CC[C@H](NC(=O)C1CCN(CC1)S(C)(=O)=O)c1ccc(F)s1

InChI Key InChIKey=PQDGWESNVKMBCV-JVLTXYAPSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 314037   

TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM314037(N-[(1S)-3-[exo-3-(3-isopropyl-5-methyl-4H-1,2,4-tr...)
Affinity DataIC50:  3.45nMAssay Description:1. HEK293 cells which can stably express CCR5 were inoculated in a 96-well plate and incubated overnight.2. The medium in each well into which cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent