BDBM31543 pyrazolo[4,3-h]quinazoline-3-carboxamide, 26
SMILES Cn1nc(C(N)=O)c2c1-c1nc(Nc3ccccc3)ncc1CC2(C)C
InChI Key InChIKey=ZLUXKRIOOANRPI-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 31543
Affinity DataIC50: 24nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Homo sapiens (Human))
Jiangnan University
Curated by ChEMBL
Jiangnan University
Curated by ChEMBL
Affinity DataIC50: 2.52E+3nMAssay Description:Inhibition of CDK6/Cyclin D3 (unknown origin) using FAM-labeled peptide as substrate after 40 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of CDK2/Cyclin A2 (unknown origin) using FAM-labeled peptide as substrate after 40 minsMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Jiangnan University
Curated by ChEMBL
Jiangnan University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of CDK4/Cyclin D3 (unknown origin) using FAM-labeled peptide as substrate after 40 minsMore data for this Ligand-Target Pair