BDBM315777 4-[5-(Difluoro- methoxy-thiazol-2- ylmethyl)-2-fluoro- phenyl]-7- morpholin-4-yl- quinazoline1H NMR (400 MHz, DMSO-d6) ppm = 9.11 (s,1H), 7.85 (d, J = 3.2, 1H), 7.81 (d, J = 3.2, 1H),7.73-7.71 (m, 2H), 7.55-7.52 (m, 2H), 7.52-7.48 (m, 1H), 7.22-6.82 (m, 3H), 3.80-3.75(m, 4H), 3.48-3.42 (m, 4H)::US10172859, Example 199::US11065253, Example 199::US9732094, Example 199
SMILES FC(F)OC(c1nccs1)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1
InChI Key InChIKey=OALIVDXCYALUSU-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 315777
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Patent
US Patent
Merck Patent
US Patent
Affinity DataKi: <1.00E+4nMAssay Description:The patch-clamp measurement was carried out at room temperature in whole-cell configuration on human embryonic kidney cells (HEK293) which have been ...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Patent
US Patent
Merck Patent
US Patent
Affinity DataKi: <1.00E+4nMAssay Description:Method for the detection and characterisation of test substances which interfere with the Kv11.1 (hERG) channel: Kv11.1 (hERG, human ether a-go-go re...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:The kinase assay was carried out in streptavidin-coated 348-well microtitre flashplates. To this end, 1.5 μg of DNA-PK/protein complex and 100 n...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:The kinase assay was carried out in streptavidin-coated 348-well microtitre flashplates. To this end, 1.5 μg of DNA-PK/protein complex and 100 n...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:The kinase assay was carried out in streptavidin-coated 348-well microtitre flashplates. To this end, 1.5 ug of DNA-PK/protein complex and 100 ng of ...More data for this Ligand-Target Pair