BDBM317045 N-{3-[4-(1-Ethyl-1H-pyrazol- 4-ylamino)-7H-pyrrolo[2,3- d]pyrimidine-5-carbonyl]- 2,4-difluoro-phenyl}-2,5- difluoro-benzenesulfonamide::US9617267, Compound P-1142

SMILES CCn1cc(Nc2ncnc3[nH]cc(C(=O)c4c(F)ccc(NS(=O)(=O)c5cc(F)ccc5F)c4F)c23)cn1

InChI Key InChIKey=VVARIPLFBATYLY-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 317045   

TargetCytochrome P450 1A2(Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM317045(N-{3-[4-(1-Ethyl-1H-pyrazol- 4-ylamino)-7H-pyrrolo...)
Affinity DataIC50: >1.00E+4nMAssay Description:The inhibition of CYP enzyme activity (IC50) for each of CYP1A2, CYP2C19, CYP2C9, CYP2D6, CYP3A4(BFC) and CYP3A4(BQ) is determined for compounds, whe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 2C19(Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM317045(N-{3-[4-(1-Ethyl-1H-pyrazol- 4-ylamino)-7H-pyrrolo...)
Affinity DataIC50: >1.00E+4nMAssay Description:The inhibition of CYP enzyme activity (IC50) for each of CYP1A2, CYP2C19, CYP2C9, CYP2D6, CYP3A4(BFC) and CYP3A4(BQ) is determined for compounds, whe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 3A4(Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM317045(N-{3-[4-(1-Ethyl-1H-pyrazol- 4-ylamino)-7H-pyrrolo...)
Affinity DataIC50: >1.00E+4nMAssay Description:The inhibition of CYP enzyme activity (IC50) for each of CYP1A2, CYP2C19, CYP2C9, CYP2D6, CYP3A4(BFC) and CYP3A4(BQ) is determined for compounds, whe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 2D6(Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM317045(N-{3-[4-(1-Ethyl-1H-pyrazol- 4-ylamino)-7H-pyrrolo...)
Affinity DataIC50: >1.00E+4nMAssay Description:The inhibition of CYP enzyme activity (IC50) for each of CYP1A2, CYP2C19, CYP2C9, CYP2D6, CYP3A4(BFC) and CYP3A4(BQ) is determined for compounds, whe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 3A4(Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM317045(N-{3-[4-(1-Ethyl-1H-pyrazol- 4-ylamino)-7H-pyrrolo...)
Affinity DataIC50: >1.00E+4nMAssay Description:The inhibition of CYP enzyme activity (IC50) for each of CYP1A2, CYP2C19, CYP2C9, CYP2D6, CYP3A4(BFC) and CYP3A4(BQ) is determined for compounds, whe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 2C9(Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM317045(N-{3-[4-(1-Ethyl-1H-pyrazol- 4-ylamino)-7H-pyrrolo...)
Affinity DataIC50: >1.00E+4nMAssay Description:The inhibition of CYP enzyme activity (IC50) for each of CYP1A2, CYP2C19, CYP2C9, CYP2D6, CYP3A4(BFC) and CYP3A4(BQ) is determined for compounds, whe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent