BDBM317194 2,3-Dimethyl-5-((1-methyl-3-(pyrrolidin-1-yl)-1H-1,2,4-triazol-5-yl)ethynyl)pyrazolo[1,5-a]pyrimidine::US9617271, 52
SMILES Cc1nn2ccc(nc2c1C)C#Cc1nc(nn1C)N1CCCC1
InChI Key InChIKey=UHFVCSZBBODTFM-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 317194
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataIC50: 2.60nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair