BDBM31803 Apogossypol derivative, 12e

SMILES Cc1cc2c(CCc3ccccc3)c(O)c(O)cc2c(O)c1-c1c(C)cc2c(CCc3ccccc3)c(O)c(O)cc2c1O

InChI Key InChIKey=BGXPXERSQBZILH-UHFFFAOYSA-N

Data  4 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 31803   

TargetBcl-2-like protein 1(Homo sapiens (Human))
Burnham Institute For Medical Research

LigandPNGBDBM31803(Apogossypol derivative, 12e)
Affinity DataIC50:  3.50E+3nM Kd:  410nMpH: 7.4 T: 2°CAssay Description:FPAs were performed using various concentrations of GST-Bcl-2 family proteins, incubated with FITC-conjugated peptide substrates in the presence of i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Burnham Institute For Medical Research

LigandPNGBDBM31803(Apogossypol derivative, 12e)
Affinity DataIC50:  5.00E+3nMT: 2°CAssay Description:FPAs were performed using various concentrations of GST-Bcl-2 family proteins, incubated with FITC-conjugated peptide substrates in the presence of i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Burnham Institute For Medical Research

LigandPNGBDBM31803(Apogossypol derivative, 12e)
Affinity DataIC50:  830nMpH: 7.4 T: 2°CAssay Description:FPAs were performed using various concentrations of GST-Bcl-2 family proteins, incubated with FITC-conjugated peptide substrates in the presence of i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Burnham Institute For Medical Research

LigandPNGBDBM31803(Apogossypol derivative, 12e)
Affinity DataIC50:  480nMpH: 7.4 T: 2°CAssay Description:FPAs were performed using various concentrations of GST-Bcl-2 family proteins, incubated with FITC-conjugated peptide substrates in the presence of i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed