BDBM318172 US10301317, Example 128::US9624228, Example 128

SMILES O=C1Nc2cc3[nH]nc(-c4ccnnc4)c3cc2CN1Cc1cccc(c1)C#N

InChI Key InChIKey=AVYXXXVXNJCCMD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 318172   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Kura Oncology

US Patent
LigandPNGBDBM318172(US10301317, Example 128 | US9624228, Example 128)
Affinity DataIC50: <50nMAssay Description:The inhibition of ERK activity by the compounds disclosed herein was determined using the Z′-LYTE kinase assay kit (Life Technologies) with a S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Kura Oncology

US Patent
LigandPNGBDBM318172(US10301317, Example 128 | US9624228, Example 128)
Affinity DataIC50: <50nMAssay Description:The inhibition of ERK activity by the compounds disclosed herein was determined using the Z′-LYTE kinase assay kit (Life Technologies) with a S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent