BDBM318194 US10301317, Example 150::US9624228, Example 150

SMILES COc1ncccc1CN1CCC[C@H](C1)N1Cc2cc3c(n[nH]c3cc2NC1=O)-c1ccnc(C)c1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 318194   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Kura Oncology

US Patent
LigandPNGBDBM318194(US10301317, Example 150 | US9624228, Example 150)
Affinity DataIC50: <50nMAssay Description:The inhibition of ERK activity by the compounds disclosed herein was determined using the Z′-LYTE kinase assay kit (Life Technologies) with a S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Kura Oncology

US Patent
LigandPNGBDBM318194(US10301317, Example 150 | US9624228, Example 150)
Affinity DataIC50: <50nMAssay Description:The inhibition of ERK activity by the compounds disclosed herein was determined using the Z′-LYTE kinase assay kit (Life Technologies) with a S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent