BDBM318431 (2S,4R)-4-((but-2-yn-1-yl)methyl)amino)-1-(2,2-diphenylacetyl)piperidine-2-carboxylic acid::US9624234, 42

SMILES CC#CCCN[C@@H]1CCN([C@@H](C1)C(O)=O)C(=O)C(c1ccccc1)c1ccccc1

InChI Key InChIKey=VARPCEUTRBZMJZ-YADHBBJMSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 318431   

TargetType-2 angiotensin II receptor(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM318431((2S,4R)-4-((but-2-yn-1-yl)methyl)amino)-1-(2,2-dip...)
Affinity DataIC50:  852nMAssay Description:120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent