BDBM318878 N-(4-(2-((4-(4-methylpiperazin-1-yl)phenyl)amino)quinazolin-8-yl)pyridin-2-yl)acrylamide::US10172868, Compound C057::US10653701, Compound C057
SMILES CN1CCN(CC1)c1ccc(Nc2ncc3cccc(-c4ccnc(NC(=O)C=C)c4)c3n2)cc1
InChI Key InChIKey=FZFASNCMJHEKIV-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 318878
Affinity DataIC50: <100nMAssay Description:(i) Peptide/Kinase Mixtures for measurement of EGFR (ErbB1):The 2×EGFR (ErbB1)/Tyr 04 mixture is prepared in 50 mM HEPES pH 7.5, 0.01% BRIJ-35, 10 mM...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair