BDBM31895 Pyrano[3,2-c]quinoline-6-chlorotacrine hybrid, 20.2HCl
SMILES Clc1ccc(cc1)-c1nc2ccc(cc2c2OCCCc12)C(=O)NCCCCCCCCNc1c2CCCCc2nc2cc(Cl)ccc12
InChI Key InChIKey=RJZPCUVMLZBWGD-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 31895
Affinity DataIC50: 7.03nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity was evaluated spectrophotometrically by the method of Ellman, using AChE from bovine or human erythrocytes and acetylthiocho...More data for this Ligand-Target Pair
Affinity DataIC50: 10.4nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity was evaluated spectrophotometrically by the method of Ellman, using AChE from bovine or human erythrocytes and acetylthiocho...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 223nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 331nMpH: 8.0 T: 2°CAssay Description:BChE inhibitory activity was evaluated spectrophotometrically by the method of Ellman, using BChE from human serum and butyrylthiocholine as substrat...More data for this Ligand-Target Pair