BDBM319153 N-[(cyclopropyl- carbamoyl) methyl]-2-[5- fluoro-6-(1- methyl-1H- indazol-6-yl)-1,3- benzothiazol- 2-yl]-2- methanesulfonyl- acetamide::US10173991, Example 196

SMILES Cn1ncc2ccc(cc12)-c1cc2sc(nc2cc1F)C(C(=O)NCC(=O)NC1CC1)S(C)(=O)=O

InChI Key InChIKey=MCRVSPHOQBTBLT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 319153   

TargetEndothelial lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM319153(N-[(cyclopropyl- carbamoyl) methyl]-2-[5- fluoro-6...)
Affinity DataIC50:  1nMAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent