BDBM319550 8-{[(2S,3S,4S)-3-Ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-2-methoxyquinoline-3-carboxamide::US10174000, Example 1

SMILES CC[C@H]1[C@@H](COc2cccc3cc(C(N)=O)c(OC)nc23)NC(=O)[C@H]1F

InChI Key InChIKey=KNLLETNQZOBJHR-SUHUHFCYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 319550   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM319550(8-{[(2S,3S,4S)-3-Ethyl-4-fluoro-5-oxopyrrolidin-2-...)
Affinity DataIC50:  2nMAssay Description:This is an in vitro assay to measure IRAK4 enzymatic activity utilizing the DELFIA (Dissociation-Enhanced Lanthanide Fluorescent Immunoassay, Perkin-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM319550(8-{[(2S,3S,4S)-3-Ethyl-4-fluoro-5-oxopyrrolidin-2-...)
Affinity DataIC50:  7.5nMAssay Description:This is an in vitro assay to measure IRAK4 enzymatic activity utilizing the DELFIA (Dissociation-Enhanced Lanthanide Fluorescent Immunoassay, Perkin-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent