BDBM319584 US10174007, Example 3::US10787438, Example 3::US10988463, Example 3

SMILES COC(=O)C[C@H]1[C@@H]2CN(C[C@H]12)c1cc(nc(n1)N1CC[C@@H]1C)C(F)(F)F

InChI Key InChIKey=QVTAJQPFFRLSHX-FIQHERPVSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 319584   

TargetKetohexokinase(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM319584(US10174007, Example 3 | US10787438, Example 3 | US...)
Affinity DataIC50:  256nMAssay Description:A 384-well format on a Corning 3653 assay plate is used, and monitored by UV-vis spectroscopy in continuous mode at rt. Compounds were prepared in DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKetohexokinase(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM319584(US10174007, Example 3 | US10787438, Example 3 | US...)
Affinity DataIC50:  3.51E+3nMAssay Description:Assay A, a 384-well format on a Corning 3653 assay plate is used, and monitored by UV-vis spectroscopy in continuous mode at rt. Compounds were prepa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKetohexokinase(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM319584(US10174007, Example 3 | US10787438, Example 3 | US...)
Affinity DataIC50:  3.51E+3nMAssay Description:Assay A, a 384-well format on a Corning 3653 assay plate is used, and monitored by UV-vis spectroscopy in continuous mode at rt. Compounds were prepa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent