BDBM32050 MLS000080844::SMR000044769::cid_663844

SMILES O=C1c2ccccc2-c2onc3ccc(NCCCn4ccnc4)c1c23

InChI Key InChIKey=SIJFRVCYVJSYJY-UHFFFAOYSA-N

Data  18 IC50  10 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 32050   

TargetGlutathione S-transferase Mu 1(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32050(MLS000080844 | SMR000044769 | cid_663844)
Affinity DataEC50:  1.72E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBcl-2-like protein 2(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32050(MLS000080844 | SMR000044769 | cid_663844)
Affinity DataEC50:  1.11E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32050(MLS000080844 | SMR000044769 | cid_663844)
Affinity DataEC50:  4.05E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
LigandPNGBDBM32050(MLS000080844 | SMR000044769 | cid_663844)
Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: 1R03MH084830-01 Project Title: TR-FRET HTS Assay for Inhibitors of MEKK2-MEK5 PB1 Domain...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
LigandPNGBDBM32050(MLS000080844 | SMR000044769 | cid_663844)
Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: 1R03MH084830-01 Project Title: TR-FRET HTS Assay for Inhibitors of MEKK2-MEK5 PB1 Domain...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32050(MLS000080844 | SMR000044769 | cid_663844)
Affinity DataEC50:  1.14E+3nMpH: 7.4 T: 2°CAssay Description:The HTS assay was conducted in 384-well microplates in a total assay volume per well of 10.1 microliters (5 microliters of bead mixture, 0.1 microlit...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay