BDBM321057 4-Amino-5-[2-(2-ethylsulfonyl-6-fluoro-phenyl) ethynyl]-7-[(2R,4S,5R)-4-hydroxy-5-[(sulfamoylamino)methyl]tetrahydrofuran-2-yl]pyrrolo[2,3-d]pyrimidine::US10174040, Example 143::US9963456, Example 143
SMILES CCS(=O)(=O)c1cccc(F)c1C#Cc1cn([C@H]2C[C@H](O)[C@@H](CNS(N)(=O)=O)O2)c2ncnc(N)c12
InChI Key InChIKey=AMTJTFJEDBMUGG-LZLYRXPVSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 321057
Affinity DataIC50: 24nMAssay Description:A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...More data for this Ligand-Target Pair