BDBM321128 (S)-2,4-dimethyl-1-((2-(methylsulfonyl)-6H-isochromeno[3,4-c]pyridin-8-yl)oxy)pentan-2-amine::US10174044, Example 59

SMILES CC(C)C[C@](C)(N)COc1ccc-2c(COc3cnc(cc-23)S(C)(=O)=O)c1

InChI Key InChIKey=XMWTVPWVVLJRAO-FQEVSTJZSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 321128   

TargetAP2-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM321128((S)-2,4-dimethyl-1-((2-(methylsulfonyl)-6H-isochro...)
Affinity DataIC50:  184nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent