BDBM321538 US10183021, Compound I-371
SMILES OC(=O)[C@@H]1Cc2ccccc2[C@@H]1Nc1nc(ncc1F)-c1cc(-c2ccon2)n(Cc2ccccc2F)n1
InChI Key InChIKey=TWVUIOUSLUZSKB-KOSHJBKYSA-N
Data 1 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 321538
TargetGuanylate cyclase soluble subunit alpha-1(Homo sapiens (Human))
Ironwood Pharmaceuticals
US Patent
Ironwood Pharmaceuticals
US Patent
Affinity DataEC50: <100nMAssay Description:Human embryonic kidney cells (HEK293), endogenously expressing soluble guanylate cyclase (sGC), were used to evaluate the activity of test compounds....More data for this Ligand-Target Pair