BDBM322176 US10183931, Example 176::US10696660, Example 176::US11311541, Example 176

SMILES O=C(Nc1cccnc1)c1cccc(c1)-c1nccc(Nc2ccc3[nH]ncc3c2)n1

InChI Key InChIKey=ICGVWDKZPPRJIA-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 322176   

TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kadmon

US Patent
LigandPNGBDBM322176(US10183931, Example 176 | US10696660, Example 176 ...)
Affinity DataIC50:  3.50E+3nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE™ Kinase Assay Kit (Invitrogen catalog number PV3793). Pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon

US Patent
LigandPNGBDBM322176(US10183931, Example 176 | US10696660, Example 176 ...)
Affinity DataIC50:  13nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE™ Kinase Assay Kit (Invitrogen catalog number PV3793). Pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent