BDBM322363 (R)-N-(2,2-dimethylquinuclidin-3-yl)-7-(2,2,2-trifluoroethyl)benzo[b]thiophene-2-carboxamide::US10183938, Compound (R)-127

SMILES CC1(C)[C@H](NC(=O)c2cc3cccc(CC(F)(F)F)c3s2)C2CCN1CC2

InChI Key InChIKey=ABQBCLMQPXYHDS-QGZVFWFLSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 322363   

TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Axovant Sciences

US Patent
LigandPNGBDBM322363((R)-N-(2,2-dimethylquinuclidin-3-yl)-7-(2,2,2-trif...)
Affinity DataKi:  505nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Axovant Sciences

US Patent
LigandPNGBDBM322363((R)-N-(2,2-dimethylquinuclidin-3-yl)-7-(2,2,2-trif...)
Affinity DataKi:  1.10E+3nMAssay Description:[3H]BRL 43694 competition binding assay was performed under contract by Cerep Poitiers, France following the methods described in Hope, A. G et al., ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent