BDBM32259 4-(6-methyl-5-imidazo[2,1-b]thiazolyl)-N-(4-methyl-2-pyridinyl)-2-thiazolamine::4-(6-methylimidazo[2,1-b][1,3]thiazol-5-yl)-N-(4-methylpyridin-2-yl)-1,3-thiazol-2-amine::MLS000034327::SMR000010233::[4-(6-Methyl-imidazo[2,1-b]thiazol-5-yl)-thiazol-2-yl]-(4-methyl-pyridin-2-yl)-amine::[4-(6-methylimidazo[2,1-b]thiazol-5-yl)thiazol-2-yl]-(4-methyl-2-pyridyl)amine::cid_644740
SMILES Cc1nc2sccn2c1-c1csc(Nc2cc(C)ccn2)n1
InChI Key InChIKey=IFAWIELOCTZGNZ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 32259
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Nmmlsc
Curated by PubChem BioAssay
Nmmlsc
Curated by PubChem BioAssay
Affinity DataEC50: 2.40E+4nMpH: 7.4 T: 2°CAssay Description:The HTS assay was conducted in 384-well microplates in a total assay volume per well of 10.1 microliters (5 microliters of bead mixture, 0.1 microlit...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
Affinity DataEC50: >5.00E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: >9.31E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
Affinity DataEC50: 1.57E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Nmmlsc
Curated by PubChem BioAssay
Nmmlsc
Curated by PubChem BioAssay
Affinity DataEC50: 1.67E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
Affinity DataEC50: 1.27E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair