BDBM324423 US10189835, Compound 699

SMILES Clc1cccc(NC(=O)N2CCc3[nH]nc(C(=O)N4CCCO4)c3C2)c1

InChI Key InChIKey=CKAITRSZSZIZQT-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 324423   

TargetCapsid protein(Hepatitis B virus)
Novira Therapeutics

Curated by ChEMBL
LigandPNGBDBM324423(US10189835, Compound 699)
Affinity DataEC50:  120nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication preincubated for 3 days follo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus genotype C subtype ayr (isolate ...)
Novira Therapeutics

US Patent
LigandPNGBDBM324423(US10189835, Compound 699)
Affinity DataEC50: <500nMAssay Description:HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent