BDBM325302 US10189841, Compound I-508::US10399980, Compound I-508

SMILES CC(C)c1ccccc1-c1ncc2[nH]c(=O)n(Cc3cnc(cn3)-n3cccn3)c2n1

InChI Key InChIKey=HQZHJBZESKMZCW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 325302   

TargetUbiquitin carboxyl-terminal hydrolase 1(Homo sapiens (Human))
Forma Therapeutics

US Patent
LigandPNGBDBM325302(US10189841, Compound I-508 | US10399980, Compound ...)
Affinity DataIC50: >2.00E+3nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 1(Homo sapiens (Human))
Forma Therapeutics

US Patent
LigandPNGBDBM325302(US10189841, Compound I-508 | US10399980, Compound ...)
Affinity DataIC50: <0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent