BDBM325806 (R)-(3-(7-amino-1-(4-phenoxyphenyl)-1H-pyrazolo[3,4-c]pyridin-3-yl)piperidin-1-yl)(3-methyloxetan-3-yl)methanone::US9637486, Example 1

SMILES CC1(COC1)C(=O)N1CCC[C@H](C1)c1nn(-c2ccc(Oc3ccccc3)cc2)c2c(N)nccc12

InChI Key InChIKey=QLUHGRCTIOLKDH-LJQANCHMSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 325806   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM325806( (R)-(3-(7-amino-1-(4-phenoxyphenyl)-1H-pyrazolo[3...)
Affinity DataIC50:  1.70nMAssay Description:In this assay, the potency (IC50) of each compound was determined from an eleven point (1:3 serial dilution; final compound concentration range in as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent