BDBM325828 4-(4-Fluorophenyl)-7-(((2S)-2-methyl-5(R)-(trifluoromethyl)piperazin-1-yl)methyl)quinoline-2-carboxamide::US9636337, 4-22- B

SMILES C[C@H]1CN[C@H](CN1Cc1ccc2c(cc(nc2c1)C(N)=O)-c1ccc(F)cc1)C(F)(F)F

InChI Key InChIKey=WEPMFGFQUDQCQI-YEJXKQKISA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 325828   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM325828(4-(4-Fluorophenyl)-7-(((2S)-2-methyl-5(R)-(trifluo...)
Affinity DataIC50:  9nMAssay Description:The utility of the compounds in accordance with the present invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM325828(4-(4-Fluorophenyl)-7-(((2S)-2-methyl-5(R)-(trifluo...)
Affinity DataIC50:  11nMAssay Description:The utility of the compounds in accordance with the present invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent