BDBM326200 3-{(3R)-1-[(2- methoxyethoxy)acetyl] piperidin-3-yl}-1-(4- phenoxyphenyl)-1H- pyrazolo[3,4-c]pyridin-7- amine::US9637486, Example 15

SMILES COCCOCC(=O)N1CCC[C@H](C1)c1nn(-c2ccc(Oc3ccccc3)cc2)c2c(N)nccc12

InChI Key InChIKey=ZITPRXFXSIQLTM-HXUWFJFHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 326200   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM326200(3-{(3R)-1-[(2- methoxyethoxy)acetyl] piperidin-3-y...)
Affinity DataIC50:  3.5nMAssay Description:In this assay, the potency (IC50) of each compound was determined from an eleven point (1:3 serial dilution; final compound concentration range in as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent