BDBM326215 1-[4-(3-fluorophenoxy)phenyl]-3-{(3R,6S)-6-methyl-1-[(3-methyloxetan-3-yl)carbonyl]piperidin-3-yl}-1H-pyrazolo[3,4-c]pyridin-7-amine::US9637486, Example 28

SMILES C[C@H]1CC[C@H](CN1C(=O)C1(C)COC1)c1nn(-c2ccc(Oc3cccc(F)c3)cc2)c2c(N)nccc12

InChI Key InChIKey=REROYALHTANKMC-RBUKOAKNSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 326215   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM326215(1-[4-(3-fluorophenoxy)phenyl]-3-{(3R,6S)-6-methyl-...)
Affinity DataIC50:  3.80nMAssay Description:In this assay, the potency (IC50) of each compound was determined from an eleven point (1:3 serial dilution; final compound concentration range in as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent