BDBM327181 1-{(1S,4S)-5-[(S)-4-(2,3-Dihydro- [1,4]dioxino[2,3-b]pyridin-3-yl)- benzyl]-2,5-diaza- bicyclo[2.2.2]oct-2-yl}-ethanone::US9662339, 264

SMILES CC(=O)N1C[C@@H]2CC[C@H]1CN2Cc1ccc(cc1)[C@H]1COc2cccnc2O1

InChI Key InChIKey=DMNPPAKBNLHVTJ-IRFCIJBXSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 327181   

TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM327181(1-{(1S,4S)-5-[(S)-4-(2,3-Dihydro- [1,4]dioxino[2,...)
Affinity DataIC50:  0.0900nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent