BDBM327187 1-{5-[(S)-4-(2,3-Dihydro- [1,4]dioxino[2,3-b]pyridin-3-yl)- benzyl]-hexahydro-pyrrolo[3,4- c]pyrrol-2-yl}-ethanone::US9662339, 270

SMILES CC(=O)N1CC2CN(Cc3ccc(cc3)[C@H]3COc4cccnc4O3)CC2C1

InChI Key InChIKey=VXMBWJLKIBRQQM-GZNCHQMQSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 327187   

TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM327187(1-{5-[(S)-4-(2,3-Dihydro- [1,4]dioxino[2,3-b]pyri...)
Affinity DataIC50:  0.140nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent