BDBM327190 US9662339, 273::{(exo)-8-[(S)-4-(2,3-Dihydro- [1,4]dioxino[2,3-b]pyridin-3-yl)- benzyl]-8-aza-bicyclo[3.2.1]oct-3- yl}-urea

SMILES NC(=O)N[C@H]1C[C@@H]2CC[C@H](C1)N2Cc1ccc(cc1)[C@H]1COc2cccnc2O1

InChI Key InChIKey=CMZILUOUJISOKH-FTEYMNFISA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 327190   

TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM327190(US9662339, 273 | {(exo)-8-[(S)-4-(2,3-Dihydro- [1...)
Affinity DataIC50:  0.160nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent