BDBM328509 (S)-1,1,1-trifluoro-2-methylpropan-2- yl (2-(acetamidomethyl)-4-((2- methoxy-4,5,6,7- tetrahydropyrazolo[1,5-a]pyridin-3- yl)sulfonyl)-3,4-dihydro-2H- benzo[b][1,4]oxazin-6-yl)carbamate::US9663502, 10AJ

SMILES COc1nn2CCCCc2c1S(=O)(=O)N1C[C@H](CNC(C)=O)Oc2ccc(NC(=O)OC(C)(C)C(F)(F)F)cc12

InChI Key InChIKey=ZIIBHFLJKYPSJG-INIZCTEOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 328509   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Lycera

US Patent
LigandPNGBDBM328509((S)-1,1,1-trifluoro-2-methylpropan-2- yl (2-(aceta...)
Affinity DataIC50:  3.61nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent